Email: laurenz(DOT)holcik(AT)univie.ac.at
Phone: ++43 +1 / 4277 - 74325

Postal address:
Center for Integrative Bioinformatics Vienna (CIBIV)
Max Perutz Labs
Dr. Bohr Gasse 9
A-1030 Wien, Austria

Research interests

• Next Generation Sequencing Data Analysis
• Cancer Subtype Discovery
• Machine Learning

Education

• Oct 2017 - Nov 2019: M.Sc. in Biotechnolgy with specialization on Bioinformatics, University of Natural Resources and Life Sciences, Vienna
• Aug 2018 - Dec 2018: Exchange Semester, University of Georgia, USA
• Oct 2014 - Jun 2017: B.Sc. in Food- and Biotechnology, University of Natural Resources and Life Sciences, Vienna

Professional experience

• Dec 2019 - present: PhD Student at the Center for Integrative Bioinformatics Vienna (CIBIV)
• Jul 2017 - Oct 2017: Internship at Boehringer Ingelheim Vienna, Bioprocess Development

Publications

in press

• J. Naas^e, M. Balmana^e, L. Holcik, M. Novatchkova, L. Dobnikar, T. Krausgruber, S. Ladstatter, C. Bock, A. von Haeseler, C. Esk, and J.A. Knoblich (in press) Quantitative profiling of human brain organoid cell diversity across four protocols and multiple cell lines. Cell Rep., 44, 116168, in press (DOI: 10.1016/j.celrep.2025.116168, PMID: 40864552)
  ^e contributed equally

2024

• N.S. Häfker, L. Holcik, A.M. Mat, A. Ćoric, K. Vadiwala, I. Beets, A.W. Stockinger, C.E. Atria, S. Hammer, R. Revilla-i-Domingo, L. Schoofs, F. Raible, and K. Tessmar-Raible (2024) Molecular circadian rhythms are robust in marine annelids lacking rhythmic behavior. PLoS Biol., 22, e3002572. (DOI: 10.1371/journal.pbio.3002572, PMID: 38603542)
• L. Holcik, A. von Haeseler, and F.G. Pflug (2024) GuaCAMOLE: GC-bias aware estimation improves the accuracy of metagenomic species abundances. bioRxiv, 2024.09.20.614100 (DOI: 10.1101/2024.09.20.614100)
• J. Naas^e, M. Balmana^e, L. Holcik, M. Novatchkova, L. Dobnikar, T. Krausgruber, S. Ladstatter, C. Bock, A. von Haeseler, C. Esk, and J.A. Knoblich (2024) Reconstitution of Human Brain Cell Diversity in Organoids via Four Protocols. bioRxiv, 2024.11.15.623576 (DOI: 10.1101/2024.11.15.623576)
  ^e contributed equally

2022

• M. Huth, L. Santini, E. Galimberti, J. Ramesmayer, F. Titz-Teixeira, R. Sehlke, M. Oberhuemer, S. Stummer, V. Herzog, M. Garmhausen, M. Romeike, A. Chugunova, K.F. Leesch, L. Holcik, K. Weipoltshammer, A. Lackner, C. Schoefer, A. von Haeseler, C. Buecker, A. Pauli, S. Ameres, A. Smith, A. Beyer, and M. Leeb (2022) NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation. Genes Dev., 36, 348-367. (DOI: 10.1101/gad.347690.120, PMID: 35241478)

2018

• V. Pfanzagl, L. Holcik, D. Maresch, G. Gorgone, H. Michlits, and P. Furtmüller (2018) Coproheme decarboxylases - Phylogenetic prediction versus biochemical experiments. Archives of biochemistry and biophysics, 2018 Feb 15;640:27-36 (DOI:10.1016/j.abb.2018.01.005)